102630-81-9

Basic information

• Product Name: 2-AMINO-N-(3,4-DIMETHYLPHENYL)BENZAMIDE
• Synonyms: 2-AMINO-N-(3,4-DIMETHYLPHENYL)BENZAMIDE;AKOS BBV-004251;OTAVA-BB 1133404;UKRORGSYN-BB BBV-004251;2-amino-N-(3,4-dimethylphenyl)benzamide(SALTDATA: FREE);CHEMBRDG-BB 5883360;AKOS BBB/072
• CAS NO: 102630-81-9
• Molecular Formula: C₁₅H₁₆N₂O
• Molecular Weight: 240.3
• Mol File: 102630-81-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 343.4°C at 760 mmHg
• Flash Point: 161.5°C
• Appearance: /
• Density: 1.182g/cm³
• Vapor Pressure: 7.05E-05mmHg at 25°C
• Refractive Index: 1.656
• CAS DataBase Reference: 2-AMINO-N-(3,4-DIMETHYLPHENYL)BENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-N-(3,4-DIMETHYLPHENYL)BENZAMIDE(102630-81-9)
• EPA Substance Registry System: 2-AMINO-N-(3,4-DIMETHYLPHENYL)BENZAMIDE(102630-81-9)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 102630-81-9(Hazardous Substances Data)

Usage

General Description

2-AMINO-N-(3,4-DIMETHYLPHENYL)BENZAMIDE is a chemical compound with the molecular formula C15H16N2O. It is an amide derivative with a benzene ring and a dimethylphenyl group attached to the amino group. 2-AMINO-N-(3,4-DIMETHYLPHENYL)BENZAMIDE has potential applications in the pharmaceutical and chemical industries, particularly in the development of drugs and organic synthesis. Its specific properties and potential uses would depend on further research and testing.

InChI:InChI=1/C15H16N2O/c1-10-7-8-12(9-11(10)2)17-15(18)13-5-3-4-6-14(13)16/h3-9H,16H2,1-2H3,(H,17,18)

Upstream product

• 102630-97-7 N-(3,4-Dimethyl-phenyl)-2-nitro-benzamide 
• 118-48-9 isatoic anhydride 
• 95-64-7 4-amino-o-xylene 
• 610-14-0 2-nitrobenzyl chloride 

Downstream Products

• 256430-31-6 3',4'-Dimethyl-2-[(ethoxycarbonyl)amino]benzanilide 
• 22874-40-4 3-(3,4-dimethylphenyl)quinazolin-4(3H)-one 
• 67117-00-4 3-(3,4-Dimethylphenyl)quinazoline-2,4(1H,3H)-dione 

Relevant articles and documents

Relationships between the chemical structure of substances and their antimycobacterial activity against atypical strains. Part 18. 3-phenyl-2H-1,3-benzoxazine-2,4(3H)-diones and isosteric 3-phenylquinazoline-2,4(1H,3H)-diones

A series of 3-phenyl-2H-1,3-benzoxazine-2,4(3H)-diones 2 and 3-phenylquinazoline-2,4(1H,3H)-diones 5 substituted on the phenyl rings were synthesized. The target compounds as well as the intermediates were tested against Mycobacterium tuberculosis, M. kansasii, and M. avium. The replacement of the oxygen atom by nitrogen resulted in a decrease or loss of antimycobacterial activity. 2-[(Ethoxycarbonyl)amino]benzanilides 4 appeared to be inactive. Salicylanilides 1 and 3-phenyl-2H-1,3-benzoxazine-2,4(3H)-diones 2 exhibit significant activity against both M. tuberculosis and nontuberculous mycobacteria (the MICs within the range of 4-250 μmol/l for all compounds). The antimycobacterial activity of the compounds increases with increasing both electron-withdrawing properties and hydrophobicity of the substituent(s) on the phenyl moiety. The antimycobacterial profile of the compounds was analyzed according to the criteria based on vector algebra, such as cosine coefficients. Moreover, salicylanilides 1 exhibit activity against other microorganisms tested by the agar diffusion method.