1026324-63-9Relevant academic research and scientific papers
An expeditious synthesis of a biscyclam with an aromatic linker
Xu, Daqiang,Mattner, Paul G.,Prasad, Kapa,Repic, Oljan,Blacklock, Thomas J.
, p. 5301 - 5304 (2007/10/03)
An efficient synthesis of 1 starting from N,N'-bis(3-aminopropyl)ethylenediamine 2 is described. Two salient features of the present work are the selective bis or tris-trifluoroacetylation of 2 and a novel bis-macrocyclization of the hexatosyl intermediate 5 using ethylene glycol ditosylate.
