1026380-17-5

Basic information

• Product Name: dipropargyl homoterephthalic acid dimethyl ester
• Synonyms: dipropargyl homoterephthalic acid dimethyl ester
• CAS NO: 1026380-17-5
• Molecular Weight: 284.312
• Mol File: 1026380-17-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: dipropargyl homoterephthalic acid dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: dipropargyl homoterephthalic acid dimethyl ester(1026380-17-5)
• EPA Substance Registry System: dipropargyl homoterephthalic acid dimethyl ester(1026380-17-5)

Safety Data

• Hazardous Substances Data: 1026380-17-5(Hazardous Substances Data)

Upstream product

• 52787-14-1 methyl 4-(2-methoxy-2-oxoethyl)benzoate 
• 106-96-7 propargyl bromide 

Downstream Products

• 146464-91-7 methyl-4-(2-((2,4-diaminopteridin-6-yl)methyl)-1-methoxy-1-oxopent-4-yn-2-yl)benzoate 

Relevant articles and documents

IMPROVED PROCESS FOR THE PREPARATION OF PRALATREXATE

An improved process for the preparation of Pralatrexate which is less hazardous. The invention further relates to novel intermediates and process thereof useful for the preparation of Pralatrexate. The present invention also relates to a substantially pure Pralatrexate and a process for obtaining the same in high yield.

Optically Pure Diastereomers of 10-Propargyl-10-Deazaaminopterin and Methods of Using Same

The present invention relates to diastereomers of 10-propargyl-10-deazaminopterin, compositions comprising optically pure diastereomers of 10-propargyl-10-deazaminopterin, in particular the two (R,S) diastereomers about the C10 position. Methods of preparation of these diastereomers, compositions containing them, and their use for the treatment of conditions related to inflammatory disorders and cancer are also disclosed.