1026417-16-2

Upstream product

• 91292-74-9 alanine ethyl ester-p-chlorobenzyl shiff base 
• 622-95-7 4-chlorobenzyl bromide 

Downstream Products

• 887766-61-2 (R)-α-methyl-4-chlorophenylalanine ethyl ester 

Relevant academic research and scientific papers

OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING -AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME

The present invention provides a chiral phase-transfer catalyst of the following formula (I): The compound (I) can be produced by reacting a 2,2'-dimethylene bromide-1,1'-biphenyl derivative, which can be produced through comparatively small number of steps, with an easily available secondary amine.

PROCESS FOR PRODUCING AMINO ACID AND DERIVATIVE THEREOF WITH OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY

A method of synthesizing an optically active amino acid and a derivative thereof in a two-phase system consisting of a water-immiscible medium and an alkaline aqueous solution using as a phase-transfer catalyst an optically active quaternary ammonium salt