10265-69-7

Usage

Uses

Used in Pharmaceutical and Agrochemical Production:
Sodium N-phenylglycinate is used as an intermediate in the production of pharmaceuticals and agrochemicals for its ability to facilitate the synthesis of various compounds.
Used in Chiral Resolution:
Sodium N-phenylglycinate is used as a chiral resolving agent for the separation of racemic mixtures, enabling the isolation of enantiomers which is crucial in the development of enantiomerically pure drugs.
Used in Organic Synthesis:
Sodium N-phenylglycinate is used as a catalyst in organic synthesis, enhancing the efficiency and selectivity of various chemical reactions.
Used in Chemical Research:
Sodium N-phenylglycinate is utilized in chemical research for its potential to contribute to the development of new chemical processes and compounds, given its versatility and effectiveness in different chemical environments.
Storage:
It is important to store sodium N-phenylglycinate in a cool, dry place away from direct sunlight and heat sources to maintain its stability and effectiveness.

InChI:InChI=1/C8H9NO2.Na/c10-8(11)6-9-7-4-2-1-3-5-7;/h1-5,9H,6H2,(H,10,11);/q;+1/p-1

Upstream product

• 3009-97-0 N-phenylglycinonitrile 
• 62-53-3 aniline 
• 2216-92-4 N-phenylglycine ethyl ester 

Downstream Products

• 63972-83-8 9-phenyl-1,4,6-trioxa-9-aza-5λ⁵-phospha-spiro[4.4]nonan-7-one 

Relevant academic research and scientific papers

Photoredox-Catalyzed α-Aminomethyl Carboxylation of Styrenes with Sodium Glycinates: Synthesis of γ-Amino Acids and γ-Lactams

A visible-light photoredox-catalyzed reductive α-aminomethyl carboxylation of styrenes with sodium glycinates and CO2 has been developed to synthesize a series of α,α-disubstituted γ-amino acids and γ-lactams with high efficiency and regioselectivity. Notably, CO2 released from the decarboxylation step can be reused for the subsequent carboxylation. Distinct from the previous reactions with the same type of substrates leading to simple decarboxylation and olefin hydroalkylation, this process involves additional CO2 sequestration, thus leading to olefin α-aminomethyl carboxylation. These findings not only provide new access to α,α-disubstituted γ-amino acids and γ-lactams but also serve as a proof of concept for CO2 reutilization in decarboxylation reactions.

A aniline acetate preparation method

The invention discloses an anilino-acetate preparation method, which comprises the steps of synthesis of n-phenylglycinenitrile, separation of n-phenylglycinenitrile, recovery of hydroxy acetonitrile and preparation of anilino-acetate. The preparation technology has the advantages of economy and environmental protection, hydroxy acetonitrile and aniline consumption can be reduced, waste water generation amount is reduced, flow is simplified, and product quality is increased.