1026517-23-6

Basic information

• Product Name: {(S)-1-[(S)-2-(tert-Butyl-dimethyl-silanyloxy)-2-phenyl-ethyl]-5-oxo-pentyl}-methyl-carbamic acid 2,2,2-trichloro-ethyl ester
• Synonyms: {(S)-1-[(S)-2-(tert-Butyl-dimethyl-silanyloxy)-2-phenyl-ethyl]-5-oxo-pentyl}-methyl-carbamic acid 2,2,2-trichloro-ethyl ester
• CAS NO: 1026517-23-6
• Molecular Weight: 524.988
• Mol File: 1026517-23-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {(S)-1-[(S)-2-(tert-Butyl-dimethyl-silanyloxy)-2-phenyl-ethyl]-5-oxo-pentyl}-methyl-carbamic acid 2,2,2-trichloro-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {(S)-1-[(S)-2-(tert-Butyl-dimethyl-silanyloxy)-2-phenyl-ethyl]-5-oxo-pentyl}-methyl-carbamic acid 2,2,2-trichloro-ethyl ester(1026517-23-6)
• EPA Substance Registry System: {(S)-1-[(S)-2-(tert-Butyl-dimethyl-silanyloxy)-2-phenyl-ethyl]-5-oxo-pentyl}-methyl-carbamic acid 2,2,2-trichloro-ethyl ester(1026517-23-6)

Safety Data

• Hazardous Substances Data: 1026517-23-6(Hazardous Substances Data)

Downstream Products

• 497-88-1 (-)-sedamine 
• 807373-52-0 2,2,2-trichloroethyl {(1S)-1-[(2S)-2-(tert-butyldimethylsilanoxy)-2-phenylethyl]-5-bromopentyl}(methyl)carbamate 
• 807373-66-6 (2S)-2-((2S)-2-{[tert-butyl(dimethyl)silyl]oxy}-2-phenylethyl)-1-methylpiperidine 
• 807373-38-2 2,2,2-trichloroethyl {(1S)-1-[(2S)-2-(tert-butyldimethylsilanoxy)-2-phenylethyl]-5-hydroxypentyl}(methyl)carbamate 

Relevant articles and documents

Indirect trapping of the retroconjugate addition reaction intermediate involved in the epimerization of lobeline: Application to the synthesis of (-)-sedamine

Alkyl chloroformates induced indirect trapping of the retroconjugate addition reaction intermediate involved in the epimerization of lobeline is described. This strategy was applied to the conversion of (-)-lobeline to (-)-sedamine in high overall yield.