1026526-48-6

Basic information

• Product Name: (3,4-Dimethoxy-benzyl)-methyl-[3-(4-nitro-phenyl)-propyl]-amine
• Synonyms: (3,4-Dimethoxy-benzyl)-methyl-[3-(4-nitro-phenyl)-propyl]-amine
• CAS NO: 1026526-48-6
• Molecular Weight: 344.411
• Mol File: 1026526-48-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3,4-Dimethoxy-benzyl)-methyl-[3-(4-nitro-phenyl)-propyl]-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (3,4-Dimethoxy-benzyl)-methyl-[3-(4-nitro-phenyl)-propyl]-amine(1026526-48-6)
• EPA Substance Registry System: (3,4-Dimethoxy-benzyl)-methyl-[3-(4-nitro-phenyl)-propyl]-amine(1026526-48-6)

Safety Data

• Hazardous Substances Data: 1026526-48-6(Hazardous Substances Data)

Upstream product

• 20716-25-0 3-(4-nitrophenyl)-1-propanol 
• 53712-77-9 1-bromo-3-(4-nitrophenyl)propane 
• 63-64-9 N-methylveratrylamine 

Downstream Products

• 143666-68-6 4-{3-[(3,4-Dimethoxy-benzyl)-methyl-amino]-propyl}-phenylamine 

Relevant articles and documents

Synthesis and Activity against Multidrug Resistance in Chinese Hamster Ovary Cells of New Acridone-4-carboxamides

A number of tricyclic carboxamides have been synthesized and tested to evaluate their ability to reverse multidrug resistance in the CHRC/5 cell line.Among them the acridone derivatives were the most potent.A key feature is the presence of a dimethoxybenzyl or phenethylamine cationic site, separated from the tricyclic lipophilic part by a carbamoylphenyl chain.Optimization led to compounds 2 orders of magnitude more active than the prototype inhibitors verapamil and amiodarone.On the basis of in vitro and in vivo activities, 9,10-dihydro-5-methoxy-9-oxo-N-phenyl>-4-acridinecarboxamide (84) has been selected for further development.