1026544-49-9

Upstream product

• 116907-30-3 (2R,5R)-2-(tert-butyl)-5-phenyl-1,3-dioxolan-4-one 
• 628-77-3 1,5-diiodopentane 
• 212627-47-9 (2R,5R)-2-(t-butyl)-5-(1-iodopent-5-yl)-5-phenyl-1,3-dioxolan-4-one 

Downstream Products

• 212627-50-4 R-(-)-ethyl α-hydroxy-α-phenyl-α-(1-tosylpenta-5-yl) acetate 
• 212627-52-6 R-(-)-ethyl α-hydroxy-α-phenyl-α-(1-mesylpenta-5-yl) acetate 
• 212627-55-9 R-(-)-ethyl α-(1-fluoropent-5-yl)-α-hydroxy-α-phenylacetate 
• 212627-48-0 R-(-)-ethyl α-hydroxy-α-(1-iodopent-5-yl)-α-phenylacetate 

Relevant academic research and scientific papers

Resolution, In vitro and In vivo evaluation of fluorine-18-labeled isomers of 1-azabicyclo[2.2.2]oct-3-yl α-(1-fluoropent-5-yl)-α-hydroxy-α- phenylacetate (FQNPe) as new PET candidates for the imaging of muscarinic- cholinergic receptor

1-Azabicyclo[2.2.2]oct-3-yl α-(1-fluoropent-5-yl)-α-hydroxy-α- phenylacetate (FQNPe, 2), an analogue of 1-azabicyclo[2.2.2]oct-3-yl α,α- (diphenyl)-α-hydroxyacetate (QNB), was resolved into its four stereoisomers. In vitro binding assays of the stereoisom