1026558-25-7Relevant academic research and scientific papers
Identification of novel ligands for the Gabapentin binding site on the α2δ subunit of a calcium channel and their evaluation as anticonvulsant agents
Bryans, Justin S.,Davies, Natasha,Gee, Nicolas S.,Dissanayake, Visaka U. K.,Ratcliffe, Giles S.,Horwell, David C.,Kneen, Clare O.,Morrell, Andrew I.,Oles, Ryszard J.,O'Toole, John C.,Perkins, Gemma M.,Singh, Lakhbir,Suman-Chauhan, Nirmala,O'Neill, Jacqueline A.
, p. 1838 - 1845 (2007/10/03)
As part of a program to investigate the structure-activity relationships of Gabapentin (Neurontin), a number of alkylated analogues were synthesized and evaluated in vitro for binding to the Gabapentin binding site located on the α2δ subunit of
