1026699-89-7

Upstream product

• 1026715-70-7 2-[Hydroxy-(5-methyl-2-m-tolyl-oxazol-4-yl)-methyl]-benzofuran-5-carbaldehyde 
• 136058-78-1 (5-Bromo-benzofuran-2-yl)-(5-methyl-2-m-tolyl-oxazol-4-yl)-methanol 
• 1026042-56-7 5-[1-{2-[Hydroxy-(5-methyl-2-o-tolyl-oxazol-4-yl)-methyl]-benzofuran-5-yl}-meth-(Z)-ylidene]-thiazolidine-2,4-dione 

Relevant academic research and scientific papers

Hypoglycemic activity of a series of α-alkylthio and α-alkoxy carboxylic acids related to ciglitazone

The thiazolidinedione moiety of ciglitazone and its analogues can be replaced by an α-alkoxy or α-thioether carboxylic acid group. The influence of the nature of the R group, the length of the connector to the aromatic backbone of the molecule, and the stereochemistry have been studied. The most potent compounds have glucose-lowering activity at doses as low as 0.01 mg/kg.