102670-63-3

Upstream product

• 817-71-0 1-bromopentan-2-one 
• 102670-98-4 tetra-n-butylammonium salt of 4-amino-5-chloro-N-<2-(diethylamino)ethyl>-2-hydroxybenzamide 
• 38059-78-8 4-amino-5-chloro-N-<2-(diethylamino)ethyl>-2-hydroxybenzamide hydrochloride 
• 364-62-5 metoclopramide 

Relevant academic research and scientific papers

ANTI-EMETIC QUINUCLIDINYL BENZAMIDES

Novel substituted benzamides of the formula STR1 wherein R. sup.1, R 2, R 3, R 4, R 5 and A are as defined herein are useful in the treatment of emesis, and particularly chemotherapy-induced emesis in cancer patients. Some of the compounds are also useful

PHARMACOLOGICALLY ACTIVE SUBSTITUTED BENZAMIDES

Novel substituted benzamides of the formula STR1 wherein R. sup.1, R 2, R 3, R 4, R 5 and A are as defined herein are useful in the treatment of emesis, and particularly chemotherapy-induced emesis in cancer patients. Some of the compounds are also useful in disorders relating to impaired gastric motility.

Substituted Benzamides. 1. Potential Nondopaminergic Antagoinists of Chemotherapy-Induced Nausea and Emesis

A series of new substituted benzamides has been synthesized and evaluated for dopamine antagonist activity and for antagonism of cisplatin-induced emesis in the dog and in the ferret.It was found that modification of the 2-methoxy substituent of metoclopr