102671-69-2Relevant academic research and scientific papers
Triazolobenzodiazepines
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, (2008/06/13)
Pharmaceutical compositions containing Triazolobenzodiazepines of the formula: STR1 are disclosed which are useful in the treatment of panic disorder or anxiety disorder.
Benzodiazepine analogs
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, (2008/06/13)
Benzodiazepine analogs of the formula: STR1 are disclosed which are antagonists of gastrin and cholecystokinin (CCK).
Benzodiazepine analogs and use as antogonists of gastrin and cholecystokinin
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, (2008/06/13)
Benzodiazepines of the formula: STR1 are disclosed which are antagonists of gastrin and cholecystokinin (CCK).
Cholestokinin Antagonists. Synthesis and Biological Evaluation of 4-Substituted 4H-Triazolobenzodiazepines
Bock, Mark G.,DiPardo, Robert M.,Evans, Ben E.,Rittle, Kenneth E.,Veber, Daniel F.,et al.
, p. 176 - 181 (2007/10/02)
A series of 4-substituted 4H-triazolobenzodiazepines was prepared by standard metodology.These compounds were tested in vitro as antagonists of the binding of cholestokinin (CCK) to rat pancreas and guinea pig brain receptors and
Triazolobenzodiazepines and pharmaceutical use
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, (2008/06/13)
Triazolobenzodiazepines of the formula: STR1 are disclosed which are antagonists of cholecystokinin (CCK).
Design of Nonpeptidal Ligands for a Peptide Receptor: Cholecystokinin Antagonists
Evans, B. E.,Rittle, K. E.,Bock, M. G.,DiPardo, R. M.,Freidinger, R. M.,et al.
, p. 1229 - 1239 (2007/10/02)
A series of 3-substituted-5-phenyl-1,4-benzodiazepines, nonpeptidal antagonists of the peptide hormone cholecystokinin (CCK), have been synthesized.Designed on the basis of facts regarding CCK, its natural-product antagonist asperlicin (3), and the antian
