102672-16-2Relevant academic research and scientific papers
2-(2-quinazolinylaminoalkoxymethyl)-1,4-dihydropyridine derivatives as cardiovascular agents
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, (2008/06/13)
Dihydropyridines of the formulae STR1 wherein R is chlorothienyl or mono- or disubstituted phenyl where said substituent is fluoro, chloro, bromo or trifluoromethyl; R1 and R2 are each alykl; R3 and R4 when taken separately are each hydrogen or alkyl; R3 and R4 when taken together with the nitrogen to which they are attached are piperidine or pyrrolidine; R5 is alkyl or 2-hydroxyethyl; R6 is hydrogen or methoxy; X and Z are each hydrogen or methoxy; Y is alkylene; R7 is chlorophenyl or trifluoromethyl-chlorophenyl; p is 0 or 1; and Q is CH or N are useful in the treatment of hypertension, heart failure and angina.
