1026722-79-1

Basic information

• Product Name: 6-deoxy-L-ribo-hexulose
• Synonyms: 6-deoxy-L-ribo-hexulose
• CAS NO: 1026722-79-1
• Molecular Weight: 164.158
• Mol File: 1026722-79-1.mol

Chemical Properties

• CAS DataBase Reference: 6-deoxy-L-ribo-hexulose(CAS DataBase Reference)
• NIST Chemistry Reference: 6-deoxy-L-ribo-hexulose(1026722-79-1)
• EPA Substance Registry System: 6-deoxy-L-ribo-hexulose(1026722-79-1)

Safety Data

• Hazardous Substances Data: 1026722-79-1(Hazardous Substances Data)

Upstream product

• 3616-21-5 6-deoxy-L-psicose 
• 10030-85-0 L-rhamnose monohydrate 

Downstream Products

• 5158-64-5 2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl bromide 

Relevant articles and documents

Photocaged Carbohydrates: Versatile Tools for Controlling Gene Expression by Light

The control of biological processes plays a central role in life science, especially the tight regulation of gene expression for biotechnological systems. In this context, optogenetic tools have emerged as an important instrument for controlling gene expression by light with high spatiotemporal resolution in a non-invasive way. Here, we present the syntheses and characterization of biofunctional photocaged carbohydrates, on the basis of the biologically most relevant carbohydrates glucose, galactose, rhamnose, and lactose. The single-step cleavage of these compounds allows both, to rapidly activate and temporary or permanently repress the transcription in E. coli after short UV-A light exposure. This study thus presents a versatile toolbox of photocaged carbohydrates for the light-triggered regulation and control of cellular processes useful for synthetic bio(techno)logy applications.

Enzymatic production of three 6-deoxy-aldohexoses from L-rhamnose

6-Deoxy-L-glucose, 6-deoxy-L-altrose, and 6-deoxy-L-allose were produced from L-rhamnose with an immobilized enzyme that was partially purified (IE) and an immobilized Escherichia coli recombinant treated with toluene (TT). 6-Deoxy-L-psicose was produced from L-rhamnose by a combination of L-rhamnose isomerase (TT-PsLRhI) and D-tagatose 3-epimerase (TT-PcDTE). The purified 6-deoxy-Lpsicose was isomerized to 6-deoxy-L-altrose and 6-deoxy-L-allose with L-arabinose isomerase (TT-EaLAI) and L-ribose isomerase (TT-AcLRI), respectively, and then was epimerized to L-rhamnulose with immobilized D-tagatose 3-epimerase (IE-PcDTE). Following purification, L-rhamnulose was converted to 6-deoxy-L-glucose with D-arabinose isomerase (TT-BpDAI). The equilibrium ratios of 6-deoxy-L-psicose:6-deoxy-L-altrose, 6-deoxy-L-psicose:6-deoxy-L-allose, and L-rhamnulose:6-deoxy-L-glucose were 60:40, 40:60, and 27:73, respectively. The production yields of 6-deoxy-L-glucose, 6-deoxy-L-altrose, and 6-deoxy-L-allose from L-rhamnose were 5.4, 14.6, and 25.1%, respectively. These results indicate that the aldose isomerases used in this study acted on 6-deoxy aldohexoses.