1026723-82-9Relevant academic research and scientific papers
Design of a potent combined pseudopeptide endothelin-a/endothelin-b receptor antagonist, ac-dBhg16-Leu-Asp-IIe-[NMe]IIe-Trp21 (PD 156252): Examination of its pharmacokinetic and spectral properties
Cody, Wayne L.,He, John X.,Reily, Michael D.,Haleen, Stephen J.,Walker, Donnelle M.,Reyner, Eric L.,Stewart, Barbra H.,Doherty, Annette M.
, p. 2228 - 2240 (2007/10/03)
The endothelins (ETs) are a family of bicyclic 21-amino acid peptides that are potent and prolonged vasoconstrictors. It has been shown that highly potent combined ET(A)/ET(B) receptor antagonists can be developed from the C- terminal hexapeptide of ET (H
