1026744-87-5Relevant academic research and scientific papers
Heterocyclic ureas: Inhibitors of acyl-CoA:cholesterol O- acyltransferase as hypocholesterolemic agents
White, Andrew D.,Creswell, Mark W.,Chucholowski, Alexander W.,Blankley, C. John,Wilson, Michael W.,Bousley, Richard F.,Essenburg, Arnold D.,Hamelehle, Katherine L.,Krause, Brian R.,Stanfield, Richard L.,Dominick, Mark A.,Neub, Martin
, p. 4382 - 4395 (2007/10/03)
A series of diaryl-substituted heterocyclic ureas was prepared, and their ability to inhibit acyl-CoA:cholesterol O-acyltransferase (ACAT) in vitro and to lower plasma total cholesterol in cholesterol-fed animal models in vivo was examined. N-(2,6-Diisopr
