1026901-65-4Relevant academic research and scientific papers
Design and synthesis of isoxazoline derivatives as factor Xa inhibitors. 1
Quan, Mimi L.,Liauw, Ann Y.,Ellis, Christopher D.,Pruitt, James R.,Carini, David J.,Bostrom, Lori L.,Huang, Peggy P.,Harrison, Kimberly,Knabb, Robert M.,Thoolen, Martin J.,Wong, Pancras C.,Wexler, Ruth R.
, p. 2752 - 2759 (1999)
Thrombosis is a major cause of mortality in the industrialized world. Therefore, the prevention of blood coagulation has become a major target for new therapeutic agents. One attractive approach is the inhibition of factor Xa (FXa), the enzyme directly re
