1026995-71-0

Basic information

• Product Name: Chloro{[(1R,2R)-(-)-2-amino-1,2-diphenylethyl](pentafluorophenylsulfonyl)amido}(p-cymene)ruthenium(II), min. 90% RuCl[(R,R)-Fsdpen](p-cymene)
• Synonyms: Chloro{[(1R,2R)-(-)-2-amino-1,2-diphenylethyl](pentafluorophenylsulfonyl)amido}(p-cymene)ruthenium(II), min. 90% RuCl[(R,R)-Fsdpen](p-cymene);Chloro{[(1R,2R)-(-)-2-amino-1,2-diphenylethyl](pentafluorophenylsulfonyl)amido}(p-cymene)ruthenium(II), min. 90% RuCl[(R,R)-Fsdpen](p-cymene);Chloro{[(1R,2R)-(-)-2-aMino-1,2-diphenylethyl](pentafluorophenylsulfonyl)aMido}(p-cyMene)rutheniuM(II),90% RuCl[(R,R)-Fsdpen](p-cyMene);Chloroaminodiphenylethylpentafluorophenylksulfonyl)-amido((p-cymene)ruthenium(II));Chloro[[(1R,2R)-(-)-2-amino-1,2-diphenylethyl](pentafluorophenylsulfonyl)amido](p-cymene)ruthenium(II);RuCl[(R,R)-FsDPEN](p-cyMene) 90%;chloro{[(lR,2R)-(-)-2-amino-l,2-diphenylethyl](pentafluorophenylsulfonyl)amido}-(p-cymene) ruthenium (II);Chloro{[(1R,2R)-(-)-2-amino-1,2-diphenylethyl](pentafluorophenylsulfonyl)amido}(p-cymene)ruthenium(II),RuCl[(R,R)-Fsdpen](p-cymene)
• CAS NO: 1026995-71-0
• Molecular Formula: C30H28ClF5N2O2RuS
• Molecular Weight: 712.135536
• Product Categories: organometallic complex;Ru
• Mol File: 1026995-71-0.mol
• Article Data: 4

Chemical Properties

• Melting Point: 238-244°C
• Flash Point: >100℃
• Appearance: orange to brown/Powder
• Storage Temp.: 2-8°C
• Sensitive: air sensitive
• CAS DataBase Reference: Chloro{[(1R,2R)-(-)-2-amino-1,2-diphenylethyl](pentafluorophenylsulfonyl)amido}(p-cymene)ruthenium(II), min. 90% RuCl[(R,R)-Fsdpen](p-cymene)(CAS DataBase Reference)
• NIST Chemistry Reference: Chloro{[(1R,2R)-(-)-2-amino-1,2-diphenylethyl](pentafluorophenylsulfonyl)amido}(p-cymene)ruthenium(II), min. 90% RuCl[(R,R)-Fsdpen](p-cymene)(1026995-71-0)
• EPA Substance Registry System: Chloro{[(1R,2R)-(-)-2-amino-1,2-diphenylethyl](pentafluorophenylsulfonyl)amido}(p-cymene)ruthenium(II), min. 90% RuCl[(R,R)-Fsdpen](p-cymene)(1026995-71-0)

Safety Data

• WGK Germany: 2
• Hazardous Substances Data: 1026995-71-0(Hazardous Substances Data)

Usage

Reaction

Catalyst used in the asymmetric transfer hydrogenation of ketones using formic acid-triethylamine mixture.

Uses

Different sources of media describe the Uses of 1026995-71-0 differently. You can refer to the following data:
1. RuCl[(R,R)-fsdpen](p-cymene) can be used as a catalyst.
2. Takasago Ligands and Complexes for Asymmetric Reactions

Upstream product

• 52462-29-0 [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂ 
• 1026785-12-5 N-((1R,2R)-2-amino-1,2-diphenylethyl)perfluorophenylsulfonamide 

Relevant articles and documents

Cleavage of N-H Bond of Ammonia via Metal-Ligand Cooperation Enables Rational Design of a Conceptually New Noyori-Ikariya Catalyst

The asymmetric transfer hydrogenation (ATH) of ketones/imines with Noyori-Ikariya catalyst represents an important reaction in both academia and fine chemical industry. The method allows for the preparation of chiral secondary alcohols/amines with very good to excellent optical purities. Remarkably, the same chiral Noyori-Ikariya complex is also a precatalyst for a wide range of other chemo- and stereoselective reductive and oxidative transformations. Among them are enantioselective sulfonamidation of acrylates (intramolecular aza-Michael reaction) and carboxylation of indoles with CO2. Development of these catalytic reactions has been inspired by the realized cleavage of the N-H bond of sulfonamides and indoles by the 16e- amido derivative of the 18e- precatalyst via metal-ligand cooperation (MLC). This paper summarizes our efforts to investigate N-H bond cleavage of gaseous ammonia in solution via MLC and reports the serendipitous discovery of a new class of chiral tridentate I3[N,N′,N″] Ru and Ir metallacycles, derivatives of the famous M-FsDPEN catalysts (M = Ru, Ir). The protonation of these metallacycles by strong acids containing weakly coordinating (chiral) anions generates ionic complexes, which were identified as conceptually novel Noyori-Ikariya precatalysts. For example, the ATH of aromatic ketones with some of these complexes proceeds with up to 99% ee.

Stereogenic: Cis -2-substituted- N -acetyl-3-hydroxy-indolines via ruthenium(ii)-catalyzed dynamic kinetic resolution-asymmetric transfer hydrogenation

Ruthenium(ii)-catalyzed dynamic kinetic resolution-asymmetric transfer hydrogenation of racemic 2-substituted-N-acetyl-3-oxoindolines to cis-2-substituted-N-acetyl-3-hydroxyindolines is reported. Using the homochiral {Ru[TfDPEN](p-cymene)} catalyst with S/C = 400 in a HCO2H/Et3N mixture, up to >99.9% ee and >99:1 dr are obtained with high yields (79-98%). This method provides the first example of preparing enantiomerically pure indolines through asymmetric transfer hydrogenation (ATH).