1027-69-6

Basic information

• Product Name: 1-(4-Methoxyphenyl)-1,3,8-triazaspiro[4.5]decan-4-one
• Synonyms: 1-(4-Methoxyphenyl)-1,3,8-triazaspiro[4.5]decan-4-one
• CAS NO: 1027-69-6
• Molecular Formula: C₁₄H₁₉N₃O₂
• Molecular Weight: 261.31956
• Mol File: 1027-69-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(4-Methoxyphenyl)-1,3,8-triazaspiro[4.5]decan-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Methoxyphenyl)-1,3,8-triazaspiro[4.5]decan-4-one(1027-69-6)
• EPA Substance Registry System: 1-(4-Methoxyphenyl)-1,3,8-triazaspiro[4.5]decan-4-one(1027-69-6)

Safety Data

• Hazardous Substances Data: 1027-69-6(Hazardous Substances Data)

Usage

General Description

1-(4-Methoxyphenyl)-1,3,8-triazaspiro[4.5]decan-4-one is a chemical compound with a complex molecular structure. It belongs to the class of spiro compounds, which are characterized by a unique carbon framework. This particular compound contains a spiro ring system with a triazaspirodecane core and a 4-methoxyphenyl group, as indicated by its name. Spiro compounds have been found to have various biological activities, making them potentially valuable for pharmaceutical and medical applications. The specific properties and uses of 1-(4-Methoxyphenyl)-1,3,8-triazaspiro[4.5]decan-4-one have not been widely documented, but its unique structure suggests that it may have interesting pharmacological properties worth further investigation.

Downstream Products

• 97861-01-3 8-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-1-(4-methoxy-phenyl)-1,3,8-triaza-spiro[4.5]decan-4-one 
• 1352949-35-9 3-((1-(4-methoxyphenyl)-4-oxo-8-(3-(2-oxobenzo[d]thiazol-3(2H)-yl)propyl)-1,3,8-triazaspiro[4.5]decan-3-yl)methyl)benzoic acid 
• 1352948-97-0 methyl 3-((1-(4-methoxyphenyl)-4-oxo-8-(3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)propyl)-1,3,8-triazaspiro[4.5]decan-3-yl)methyl)benzoate 
• 1352949-36-0 methyl 3-((1-(4-methoxyphenyl)-4-oxo-8-(3-(2-oxobenzo[d]thiazol-3(2H)-yl)propyl)-1,3,8-triazaspiro[4.5]decan-3-yl)methyl)benzoate 
• 1352948-98-1 tert-butyl 3-(3-(methoxycarbonyl)benzyl)-1-(4-methoxyphenyl)-4-oxo-1,3,8-triazaspiro[4.5]decane-8-carboxylate 
• 1352949-00-8 tert-butyl-1-(4-methoxyphenyl)-4-oxo-1,3,8-triazraspiro[4.5]decane-8-carboxylate 
• 851338-67-5 rac-1-(4-methoxy-phenyl)-8-(2-oxo-cyclohexyl)-1,3,8-triaza-spiro[4.5]decan-4-one 

Relevant articles and documents

TRIAZA-SPIROPIPERIDINE DERIVATIVES FOR USE AS GLYT-1 INHIBITORS IN THE TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS

The invention relates to compounds of the general formula (I), wherein A-A is -CH2-CH2-, -CH2-CH2-CH2-, -CH2-0- or -0-CH2-; x is hydrogen or hydroxy; R1 is aryl or heteroaryl, unsubstituted or substituted by one or more substituents, selected from the group consisting of lower alkyl, lower alkoxy, halogen or trifluoromethyl; R2 is aryl or heteroaryl, unsubstituted or substituted by one or more substituents, selected from the group consisting of lower alkyl, lower alkoxy, halogen or trifluoromethyl, or is lower alkyl, -(CH2)n--cycloalkyl, -(CH2)n-CF3, -(CH2)p-0-lower alkyl, -(CH2)1,2-phenyl, optionally substituted by halogen, lower alkyl, lower alkoxy or trifluoromethyl, or is -(CH2)p-NRR", wherein W and R" form together with the N-atom a heterocyclic ring, selected from the group consisting of piperidine, morpholine, thiomorpholine or 1, I-dioxo thiomorpholine; R3, R4 are independently from each other hydrogen, lower alkyl, phenyl or benzyl; R5 is hydrogen, lower alkyl or benzyl; R6 is hydrogen or lower alkyl; n is 0, 1 or 2; and p is 2 or 3; and to pharmaceutically acceptable acid addition salts thereof for the treatment of psychoses, pain, neurodegenerative disfunction in memory and learning, schizophrenia, dementia and other diseases in which cognitive processes are impaired, such as attention deficit disorders or Alzheimer's disease.