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Tolpentamide, also known as Tolbutamide, is a sulfonylurea class of medication primarily used to treat type 2 diabetes by stimulating the release of insulin from the pancreas. It works by binding to the sulfonylurea receptor on pancreatic beta cells, which in turn triggers the closure of ATP-sensitive potassium channels, leading to membrane depolarization and calcium influx. This process ultimately results in the exocytosis of insulin-containing vesicles, thereby lowering blood glucose levels. Tolpentamide is an oral hypoglycemic agent that is generally well-tolerated, but it may cause side effects such as hypoglycemia, gastrointestinal issues, and allergic reactions. It is important to note that tolpentamide is not suitable for treating type 1 diabetes or diabetic ketoacidosis.

1027-87-8

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1027-87-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1027-87-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,2 and 7 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1027-87:
(6*1)+(5*0)+(4*2)+(3*7)+(2*8)+(1*7)=58
58 % 10 = 8
So 1027-87-8 is a valid CAS Registry Number.
InChI:InChI=1/C13H18N2O3S/c1-10-6-8-12(9-7-10)19(17,18)15-13(16)14-11-4-2-3-5-11/h6-9,11H,2-5H2,1H3,(H2,14,15,16)

1027-87-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-cyclopentyl-3-(4-methylphenyl)sulfonylurea

1.2 Other means of identification

Product number -
Other names N-p-Tolylsulfonyl-N'-cyclopentyl-harnstoff

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1027-87-8 SDS

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