1027008-46-3

Basic information

• Product Name: methyl (E)-2-{1-[2-(anilinocarbonyl)hydrazono]ethyl}-6-(dimethylamino)-4-oxo-5-hexenoate
• Synonyms: methyl (E)-2-{1-[2-(anilinocarbonyl)hydrazono]ethyl}-6-(dimethylamino)-4-oxo-5-hexenoate
• CAS NO: 1027008-46-3
• Molecular Weight: 360.413
• Mol File: 1027008-46-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl (E)-2-{1-[2-(anilinocarbonyl)hydrazono]ethyl}-6-(dimethylamino)-4-oxo-5-hexenoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (E)-2-{1-[2-(anilinocarbonyl)hydrazono]ethyl}-6-(dimethylamino)-4-oxo-5-hexenoate(1027008-46-3)
• EPA Substance Registry System: methyl (E)-2-{1-[2-(anilinocarbonyl)hydrazono]ethyl}-6-(dimethylamino)-4-oxo-5-hexenoate(1027008-46-3)

Safety Data

• Hazardous Substances Data: 1027008-46-3(Hazardous Substances Data)

Upstream product

• 94126-55-3 Methyl 3-(phenylaminocarbonylazo)-2-butenoate 
• 194233-66-4 (1E)-3-{[tert-butyl(dimethyl)silyl]oxy}-N,N-dimethyl-1,3-butadien-1-amine 

Relevant articles and documents

Flexible protocol for the chemo- and regioselective building of pyrroles and pyrazoles by reactions of Danishefsky's dienes with 1,2-diaza-1,3-butadienes

The versatility of the Mukaiyama-Michael-type addition/heterocyclization of Danishefsky's diene with 1,2-diaza-1,3-butadienes was applied to the synthesis of both 4H-1-aminopyrroles and 4.5H-pyrazoles. Thus, the same reagents furnished different types of highly functionalized azaheterocycles essentially depending on their structure: as a matter of fact, R1 = COOR or CONR2 differently affects the acidity of the proton at the adjacent carbon. An unexpected formation of 5H-1-aminopyrroles from the reactions carried out in water was also observed.