1027013-54-2

Upstream product

• 157422-73-6 N-allyl-2,2-diethoxy-1-phenylethylamine 
• 106746-09-2 3(RS)-amino-1,1,1-trifluoro-2(RS)-hydroxy-4-methylpentane hydrochloride 
• 6175-45-7 2,2-diethoxyacetophenone 
• 1026076-48-1 2-(9-Benzyl-8-benzyloxy-1-oxo-3-phenyl-1,9-dihydro-β-carbolin-2-yl)-N-(3,3,3-trifluoro-2-hydroxy-1-isopropyl-propyl)-acetamide 

Downstream Products

• 1027427-93-5 Trifluoro-methanesulfonic acid 9-benzyl-1-oxo-3-phenyl-2-[(3,3,3-trifluoro-2-hydroxy-1-isopropyl-propylcarbamoyl)-methyl]-2,9-dihydro-1H-β-carbolin-8-yl ester 
• 1026494-28-9 {9-Benzyl-1-oxo-3-phenyl-2-[(3,3,3-trifluoro-2-hydroxy-1-isopropyl-propylcarbamoyl)-methyl]-2,9-dihydro-1H-β-carbolin-8-yl}-phosphonic acid dimethyl ester 
• 161488-63-7 2-<8-(dimethoxyphosphoryl)-1-oxo-3-phenyl-1,2-dihydropyrido<3,4-b>indol-2-yl>-N-(3,3,3-trifluoro-2-hydroxy-1-isopropylpropyl)acetamide 

Relevant academic research and scientific papers

Non-peptidic Inhibitors of Human Leukocyte Elastase. 4. Design, Synthesis, and in Vitro and in Vivo Activity of a Series of β-Carbolinone-Containing Trifluoromethyl Ketones

A novel series of human leukocyte elastase (HLE) inhibitors containing the β-carbolinone ring system are reported.The design of these trifluoromethyl ketone-based inhibitors used a combination of structural information obtained from X-ray crystallography