1027014-25-0

Upstream product

• 100-84-5 1-methoxy-3-methyl-benzene 
• 94060-00-1 4-methoxy-2-methylcyclohex-1-ene 
• 31883-98-4 3-methylcyclohex-3-en-1-one 

Downstream Products

• 157330-41-1 4-[2-Bromo-6-methoxy-3-((E)-2-phenylsulfanyl-vinyl)-phenoxy]-3-methyl-cyclohex-2-enone 
• 157330-39-7 (Z)-3-[2-Bromo-4-methoxy-3-(2-methyl-4-oxo-cyclohex-2-enyloxy)-phenyl]-acrylonitrile 
• 157330-40-0 (E)-3-[2-Bromo-4-methoxy-3-(2-methyl-4-oxo-cyclohex-2-enyloxy)-phenyl]-acrylonitrile 
• 1333144-39-0 methyl 2-{benzyl[2-methyl-4-oxocyclohex-2-en-1-yl]carbamoyl}pent-4-enoate 
• 1333144-37-8 4-(benzylamino)-3-methylcyclohex-2-en-1-one 
• 1357266-48-8 4-[(2,2-dimethoxyethyl)amino]-3-methylcyclohex-2-en-1-one 
• 1357267-10-7 methyl (6E)-2-[(4-methoxybenzyl)(2-methyl-4-oxocyclohex-2-en-1-yl)carbamoyl]-7-phenylhept-6-en-4-ynoate 
• 1357267-09-4 methyl 5-(4-chlorophenyl)-2-[(2,2-dimethoxyethyl)(2-methyl-4-oxocyclohex-2-en-1-yl)carbamoyl]pent-4-ynoate 
• 1357267-08-3 methyl 2-[(4-methoxybenzyl)(2-methyl-4-oxocyclohex-2-en-1-yl)carbamoyl]-5-(4-methylphenyl)pent-4-ynoate 
• 1357267-07-2 methyl 2-[(4-methoxybenzyl)(2-methyl-4-oxocyclohex-2-en-1-yl)carbamoyl]-5-phenylpent-4-ynoate 
• 1357267-05-0 methyl 2-[4-methoxybenzyl(2-methyl-4-oxocyclohex-2-en-1-yl)carbamoyl]hex-5-ynoate 

Relevant academic research and scientific papers

Alkali base-initiated Michael addition/alkyne carbocyclization cascades

A new cascade reaction involving an intramolecular Michael addition followed by an alkyne carbocyclization is presented. The reaction is promoted by a substoichiometric amount of KHMDS and represents one of the rare examples where the carbocyclization of

Expedient route to the functionalized calyciphylline a- Type skeleton via a michael addition- RCM strategy

An efficient, robust, and scalable strategy to access the functionalized core of calyciphylline A-type alkaloids has been developed starting from commercially available 3-methylanisole. Key features of this approach are an intramolecular Michael addition/allylation sequence and a ringclosing metathesis step.

The Radical Cyclization Approach to Morphine. Models for Highly Oxygenated Ring-III Synthons

4-Iodo-3-methyl-2-cyclohexenone (9) and 3-alkyl 3-cyclohexene-1,2-diol derivatives 16 were examined as ring-III equivalents for the tandem radical cyclization approach to the synthesis of morphine (1a).