10271-74-6Relevant academic research and scientific papers
An efficient and convenient synthesis of N-substituted amides under heterogeneous condition using Al(HSO4)3 via Ritter reaction
Karimian, Elnaz,Akhlaghinia, Batool,Ghodsinia, Sara S.E.
, p. 429 - 439 (2016/03/16)
An efficient and inexpensive synthesis of N-substituted amides from the reaction of aliphatic and aromatic nitriles with various benzylic alcohols (secondary and tertiary) and tert-butyl alcohol by refluxing nitromethane via the Ritter reaction catalyzed by aluminum hydrogen sulfate [Al(HSO4)3] is described. The catalyst which is an air-stable, cost-effective solid acid could be readily recycled by filtration and reused four times without any significant loss of its activity. [Figure not available: see fulltext.]
