1027139-77-0Relevant academic research and scientific papers
Facile and efficient bromination of benz[F]Indan-1-One
Unlu, Cihansel Sancak,Tutar, Ahmet,Erenler, Ramazan
experimental part, p. 705 - 708 (2012/09/07)
The bromination reaction of benz[f]indan-1-one was investigated by NBS, molecular bromine and fotobromination. Benz[f]indan-1-one was synthesized by treatment of α,α,α',α'- tetrabromo-o-xylene with cyclopenten-1-one. Bromination of benz[f]indan-1-one with bromine (1.2 equiv) at low temperature afforded the α-monobromobenz[f]indanone in addition to α,α'- dibromobenz[f]indanone. The quantitative yield of α,α'-dibromobenz[f]indanone was synthesized by treatment of benz[f]indan-1-one with 2.1 equv. bromine at room temperature for 25 min. The electrophonic bromination of α,α'-dibromobenz[f]indanone with N-bromosuccinimide (NBS) regioselectively proceeded at C-8 side and afforded the corresponding 2,2,8- Tribromobenz[f]indanone which also could be obtained from the treatment of benz[f]indan-1-one with NBS and SiO2. Dibromobenz[f]indenone was generated by the treatment of benz[f]indan-1-one with bromine in photochemical reaction apparatus irradiated by 150 watt projection lamp. Dibromobenz[f]indenone was also synthesized by the treatment of α,α'-dibromobenz[f]indanone with NBS in photochemical reaction apparatus irradiated by 150 watt projection lamp. 2,8- Dibromobenz[f]indanone was synthesized by the reaction of α-monobromobenz[f]indanone with NBS.
