1027154-36-4Relevant academic research and scientific papers
4-Benzyl- and 4-benzoyl-3-dimethylaminopyridin-2(1H)-ones, a new family of potent anti-HIV agents: Optimization and in vitro evaluation against clinically important HIV mutant strains
Benjahad, Abdellah,Courté, Karine,Guillemont, Jér?me,Mabire, Dominique,Coupa, Sophie,Poncelet, Alain,Csoka, Imre,Andries, Koen,Pauwels, Rudi,De Béthune, Marie-Pierre,Monneret, Claude,Bisagni, Emile,Nguyen, Chi Hung,Grierson, David S.
, p. 5501 - 5514 (2007/10/03)
The 4-benzyl and 4-benzoyl-3-dimethylaminopyridinones 13 and 14 are representatives of a new class of highly potent non nucleoside type inhibitors of HIV-1 reverse transcriptase. To conduct SAR studies on these two lead compounds, 102 new analogues were p
