102717-31-7

Upstream product

• 102717-29-3 (5S)-5-({[tert-butyl(diphenyl)silyl]oxy}methyl)dihydrofuran-2(3H)-one 
• 79580-60-2 (3R,4S,5R)-3,4-diacetoxy-5-acetoxymethyl-2-tetrahydrofuranone 
• 82796-87-0 D-xylono-1,5-lactone 
• 79580-65-7 3β-acetoxy-5β-acetoxymethyltetrahydrofuran-2-one 
• 87-72-9 D-Xylose 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 19473-20-2 (3S,5S)-(+)-3-hydroxy-5-hydroxymethyl-tetrahydrofuran-2-one 

Downstream Products

• 162889-21-6 (3S,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-3-(2-methoxy-ethoxymethoxy)-dihydro-furan-2-one 
• 162889-26-1 1α-di<(2-methoxyethoxy)methoxy>vitamin D₃ 
• 166450-62-0 (2S,4S)-5-(tert-Butyl-diphenyl-silanyloxy)-4-hydroxy-2-(2-methoxy-ethoxymethoxy)-pentanal 
• 41294-56-8 1α-hydroxyvitamin D3 
• 152963-78-5 1-O-acetyl-5-O-(t-butyldiphenylsilyl)-2,3-dideoxy-2-fluoro-D-erythro-pentafuranose 
• 152963-76-3 (3R,5S)-5-({[tert-butyl(diphenyl)silyl]oxy}methyl)-3-fluorodihydrofuran-2(3H)-one 

Relevant academic research and scientific papers

A General Synthetic Route to A-Ring Hydroxylated Vitamin D Analogs from Pentoses

The enyne needed for coupling to a CD-ring fragment, namely, 3S,5R-oct-1-en-7-yne-3,5-diol, in the Trost-Dumas carbopalladation route to 1α,25-dihydroxyvitamin D3 was synthesized from D-xylose in 13 steps and 21percent yield.

Synthesis of 2-fluoro sugar and its condensation reaction with silylated thymine

2,3-Dideoxy-2-fluoro-D-erythro-pentofuranose was easily prepared from 3-DPA lactone. The condensation reaction between 1-O-acetyl derivative of this sugar and silylated thymine in the presence of TMSOTf proceeded in a poorly stereoselective manner.

The Synthesis of the δ-Lactone Portion of the Mevinic Acids; a New Non-acidic Method of Cyclic Lactone Expansion

An alkoxy-mercuration demercuration sequence has been used as the key step in an enantiospecific synthesis of a protected synthon for the lactone portion of the mevinic acids.

A Tactically Novel Alternative to Acyclic Stereoselection Based on the Concept of a Replicating Chiron - Access to 1,3-Polyols

(S)-Glutamic acid is used as a chiral template to construct seven carbon subunits containing alternating hydroxyl groups with stereochemical control.Enantiomeric and/or diastereomeric 3,5-dideoxy-heptitols are thus obtained.