1027178-82-0

Upstream product

• 335239-70-8 4-(tert-butyl-dimethyl-silanyloxy)-1-phenyl-pentan-3-one 
• 335239-78-6 tert-butyl-(3,3-difluoro-1-methyl-2-phenethyl-allyloxy)-dimethyl-silane 

Downstream Products

• 335239-98-0 (E)-2-(2-phenylethyl)but-2-enoyl fluoride 
• 335239-85-5 Methanesulfonic acid (E)-1,1-difluoro-2-phenethyl-but-2-enyl ester 

Relevant academic research and scientific papers

Mesyloxy-group migration as the stereoselective preparation method of various functionalized olefins and its reaction mechanism

It was demonstrated that mesylation of appropriate γ,γ-difluorinated allylic alcohols under usual conditions furnished the corresponding α,γ-difluorinated allylic mesylates, possibly by way of 1,3-mesyloxy-group migration after formation of the expected "normal" intermediates, γ,γ-difluorinated allylic mesylates. This rearrangement was conveniently applied to the construction of trisubstituted allylic alcohols, α,β-unsaturated esters, amides, or ketones in good to excellent chemical yields with exclusive E selectivities.