102718-20-7Relevant academic research and scientific papers
Heterocyclization of thiocarbonohydrazides: Facile synthesis of 5-unsubstituted-1,3,4-thiadiazoles
Hassan, Alaa A.,Abdel-Latif, Fathy F.,Aziz, Mohamed Abdel,Mostafa, Sara M.,Br?se, Stefan,Nieger, Martin
, p. 1183 - 1186 (2015)
2-(Hydrazinecarbothioyl)-N-substituted hydrazinecarbothioamides react with 2,3,5,6-tetrachloro-1,4-benzoquinone in high yields in a novel fast and facile method to give 5-unsubstituted-1,3,4-thiadiazole-2-amine derivatives. The synthesized compounds were characterized by spectroscopic methods and confirmed by using X-ray crystallography. A rationale for the formation of the products is presented.
