1027195-94-3Relevant academic research and scientific papers
Synthesis, structures and biological activity of some N1-substituted 4-oxocinnolines.
Stanczak,Kwapiszewski,Ochocki,Lewgowd,Szadowska,Pakulska,Glowka
, p. 113 - 121 (2007/10/02)
The method of preparation of N1-substituted 4-hydroxycinnolines is described, by alkylation with methyl bromopropionate of the corresponding 4-hydroxycinnolines. The obtained esters were further converted into amides and hydrazides. The effect of several synthesized derivatives on central nervous system was studied. The structure of some of them was confirmed by the X-ray analysis.
