1027220-19-4Relevant academic research and scientific papers
Rational design, synthesis, and biological activity of benzoxazinones as novel factor Xa inhibitors
Dudley,Bunker,Chi,Cody,Holland,Ignasiak,Janiczek-Dolphin,McClanahan,Mertz,Narasimhan,Rapundalo,Trautschold,Van Huis,Edmunds
, p. 4063 - 4070 (2007/10/03)
Inappropriate thrombus formation within blood vessels is the leading cause of mortality in the industrialized world. Factor Xa (FXa) is a trypsin-like serine protease that plays a key role in the blood coagulation cascade and represents an attractive targ
