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1027254-01-8

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1027254-01-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1027254-01-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,7,2,5 and 4 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1027254-01:
(9*1)+(8*0)+(7*2)+(6*7)+(5*2)+(4*5)+(3*4)+(2*0)+(1*1)=108
108 % 10 = 8
So 1027254-01-8 is a valid CAS Registry Number.

1027254-01-8Downstream Products

1027254-01-8Relevant academic research and scientific papers

INHIBITORS OF KINASE ACTIVITY

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Page/Page column 98, (2008/12/05)

The present invention relates to pyridines or pyrazines that inhibit kinases. In particular the compounds of the invention inhibit members of the class III PTK receptor family such as FMS (CSF-IR), c-KIT, PDGFRβ, PDGFRα or FLT3 and KDR, SRC, EphA2, EphA3, EphA8, FLTl, FLT4, HCK, LCK, PTK5 (FRK), SYK, DDRl and DDR2 and RET. The compounds of the invention are useful in the treatment of kinase associated diseases such as immunological and inflammatory diseases; hyperproliferative diseases including cancer and diseases involving neo-angiogenesis; renal and kidney diseases; bone remodeling diseases; metabolic diseases; and vascular diseases.

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