1027263-80-4

Upstream product

• 7569-58-6 2-(3-chloro-4-methoxyphenyl)acetonitrile 
• 104-47-2 p-methoxybenzylnitrile 
• 7569-87-1 3-chloro-4-methoxyphenethylamine 
• 1026415-09-7 N-[2-(3-chloro-4-methoxy-phenyl)-ethyl]-2,6-dimethyl-benzamide 

Downstream Products

• 1026343-25-8 6-chloro-1-(2,6-dimethyl-phenyl)-7-methoxy-2-methyl-1,2,3,4-tetrahydro-isoquinoline 
• 1026596-21-3 6-chloro-1-(2,6-dimethyl-phenyl)-7-methoxy-1,2,3,4-tetrahydro-isoquinoline 

Relevant academic research and scientific papers

Quantitative structure-activity relationship modeling of dopamine D1 antagonists using comparative molecular field analysis, genetic algorithms- partial least-squares, and K nearest neighbor methods

Several quantitative structure-activity relationship (QSAR) methods were applied to 29 chemically diverse D1 dopamine antagonists. In addition to conventional 3D comparative molecular field analysis (CoMFA), cross-validated R2 guided