1027283-80-2

Upstream product

• 81135-31-1 (4S,5R,1'R,3'E)-2,2,3-trimethyl-5-(1'-methyl-3'-pentenyl)-4-oxazolidinecarboxylic acid 
• 59865-23-5 (2S,3R,4R,6E)-3-hydroxy-4-methyl-2-methylamino-6-octenoic acid 

Relevant academic research and scientific papers

Cyclosporin analogs modified in the 3,7,8-positions: Substituent effects on peptidylprolyl isomerase inhibition and immunosuppressive activity are nonadditive

Four analogs of cyclosporin A (CsA) were synthesized to determine if the biological activities of CsA analogs generated by multiple amine acid replacements are predictable from the effects on biological activity of analogs with single residue changes. CsA