1027294-98-9Relevant academic research and scientific papers
4-(Phenylsulfonyl)piperidines: Novel, selective, and bioavailable 5-HT2A receptor antagonists
Fletcher, Stephen R.,Burkamp, Frank,Blurton, Peter,Cheng, Susan K. F.,Clarkson, Robert,O'Connor, Desmond,Spinks, Daniel,Tudge, Matthew,Van Niel, Monique B.,Patel, Smita,Chapman, Kerry,Marwood, Rose,Shepheard, Sara,Bentley, Graham,Cook, Gina P.,Bristow, Linda J.,Castro, Jose L.,Hutson, Peter H.,MacLeod, Angus M.
, p. 492 - 503 (2007/10/03)
On the basis of a spirocyclic ether screening lead, a series of acyclic sulfones have been identifed as high-affinity, selective 5-HT2A receptor antagonists. Bioavailability lacking in the parent, 1-(2-(2,4-difluorophenyl)ethyl)-4-(phenylsulfon
