1027298-17-4Relevant articles and documents
Potent and orally active angiotensin II receptor antagonists with equal affinity for human AT1 and AT2 subtypes
Chang,Ashton,Flanagan,Chen,O'Malley,Zingaro,Kivlighn,Siegl,Lotti,Chang,Greenlee
, p. 3741 - 3758 (2007/10/03)
In order to block the effects induced by the interactions between angiotensin II (AII) and both AT1 and AT2 receptors, we have pursued the discovery of orally active non-peptide AII antagonists that exhibit potent and equal affinity