1027321-28-3

Basic information

• Product Name: (R)-5-[(4-methoxyphenyl)aminomethyl]-1,3-oxazolidin-2-one
• Synonyms: (R)-5-[(4-methoxyphenyl)aminomethyl]-1,3-oxazolidin-2-one
• CAS NO: 1027321-28-3
• Molecular Weight: 222.244
• Mol File: 1027321-28-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-5-[(4-methoxyphenyl)aminomethyl]-1,3-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-5-[(4-methoxyphenyl)aminomethyl]-1,3-oxazolidin-2-one(1027321-28-3)
• EPA Substance Registry System: (R)-5-[(4-methoxyphenyl)aminomethyl]-1,3-oxazolidin-2-one(1027321-28-3)

Safety Data

• Hazardous Substances Data: 1027321-28-3(Hazardous Substances Data)

Relevant articles and documents

Regioselective and stereospecific synthesis of enantiopure 1,3-oxazolidin-2-ones by intramolecular ring opening of 2-(Boc-aminomethyl) aziridines. Preparation of the antibiotic linezolid

The amide moiety of several enantiopure unactivated 1-aryl- or 1-alkylaziridine-2-carboxamides were reduced and then W-Boc-protected to afford enantiopure 2-(Boc-aminomethyl)aziridines, which were further converted into enantiopure 5-(aminomethyl)-1,3-oxazolidin-2-ones by means of a stereospecific and fully regioselective BF3-Et2O-promoted intramolecular nucleophilic ring opening. One of these oxazolidinones was transformed into the antibiotic linezolid through a Cul-catalyzed N-arylation reaction at its carbamate moiety.