1027343-58-3

Basic information

• Product Name: Ethyl (1R,2R,3S,5R)-2-amino-6,6-dimethylbicyclo[3.1.1]heptan-3-carboxylate hydrochloride
• Synonyms: Ethyl (1R,2R,3S,5R)-2-amino-6,6-dimethylbicyclo[3.1.1]heptan-3-carboxylate hydrochloride
• CAS NO: 1027343-58-3
• Molecular Formula: C12H22ClNO2
• Molecular Weight: 247.76158
• Mol File: 1027343-58-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethyl (1R,2R,3S,5R)-2-amino-6,6-dimethylbicyclo[3.1.1]heptan-3-carboxylate hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl (1R,2R,3S,5R)-2-amino-6,6-dimethylbicyclo[3.1.1]heptan-3-carboxylate hydrochloride(1027343-58-3)
• EPA Substance Registry System: Ethyl (1R,2R,3S,5R)-2-amino-6,6-dimethylbicyclo[3.1.1]heptan-3-carboxylate hydrochloride(1027343-58-3)

Safety Data

• Hazardous Substances Data: 1027343-58-3(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 1027343-54-9 (1R,2R,5S,7R)-8,8-dimethyl-3-azatricyclo[5.1.1.0(2,5)]nonan-4-one 
• 1027343-50-5 (1R,2R,5S,7R)-2-amino-6,6-dimethylbicyclo[3.3.1]heptane-3-carboxylic acid hydrochloride 

Relevant articles and documents

CHIRAL CYCLIC ?-AMINO ACIDS AND THEIR DERIVATES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THE USE OF SUCH COMPOUNDS

The invention relates to chiral cyclic β-amino acids of Formula (I) and their salts formed with pharmaceutically acceptable acids or bases, wherein the main meanings of the substituents are as follows: R stands for C1-4 Alk; X stands for -COOH, -CONH2, -CONH(C1-4 Alk), -CON(C1-4 Alk)2, -COO(C1-4 Alk), -COPhe-O-(C1-4 Alk) or -CH2OH; Y stands for -NH2, -NHBoc, -NHFmoc, -NH(C1-4 Alk), -N(C1-4 Alk)2, -NHCH2Ph, or Ar-NH-C(=X0)-N(R0)- wherein Ar stands for a phenyl group substituted by C1-4 alkoxy or halogen, X0 stands for O or S, and R0 stands for hydrogen or benzyl; and X + Y stands for -CONH- vagy -CON(Boc)-; with the proviso that when X stands for -COOH, then Y may be only different from -NH2. The invention also relates to pharmaceutical compositions having multidrug-resistance reversing effect that contain one or more compound(s) of Formula (I) or a salt thereof and inert pharmaceutical carriers and/or auxiliary agents. The invention also relates to carboxylic acids of Formula (XX) and their salts.