1027381-97-0Relevant articles and documents
tert-Butyldimethylsilyloxytrichloromethylmethane-readily accessible and robust protecting group for (hetero)aryl aldehydes
Cafiero, Lauren R.,Snowden, Timothy S.
, p. 2844 - 2847 (2008/09/20)
The tert-butyldimethylsilyloxytrichloromethylmethane (TBSTCM) substituent serves as a readily accessible masking group for aromatic and heteroaromatic aldehydes. The TBSTCM substituent is compatible with a range of common reagents and offers several strategic advantages over alternative aldehyde protecting groups.