102739-74-2Relevant academic research and scientific papers
Synthesis of chiral N,N'-disubstituted 1,2-benzenediamines from o- dibromobenzene
Rivas, Felix M.,Riaz, Uzma,Diver, Steven T.
, p. 1703 - 1707 (2000)
Palladium-catalyzed amination of o-dibromobenzene provided chiral N,N'- disubstituted 1,2-benzenediamines in good to excellent yields. The amination was executed stepwise and in one pot to give unsymmetrically and symmetrically substituted 1,2-benzenediamines. Incorporation of chiral primary amines was possible without racemization using catalytic Pd2dba3- BINAP. (C) 2000 Elsevier Science Ltd.
Palladium-catalyzed multiple aryl animations of polybromobenzenes
Witulski, Bernhard,Senft, Stefan,Thum, Andreas
, p. 504 - 506 (2007/10/03)
Morpholinobenzenes with up to four N-morpholino groups have been synthesized efficiently from the corresponding bromobenzenes via palladium catalyzed multiple aryl amination reactions. Surprisingly, hexabromobenzene (1) yielded selectively 1,2,4,5-(N,N,N,N)-tetra-(23) and 1,3,5-(N,N,N)-trimorpholinobenzene (14).
