1027400-20-9

Basic information

• Product Name: C₃₁H₂₅N₃O
• CAS NO: 1027400-20-9
• Molecular Weight: 455.559
• Mol File: 1027400-20-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₁H₂₅N₃O(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₁H₂₅N₃O(1027400-20-9)
• EPA Substance Registry System: C₃₁H₂₅N₃O(1027400-20-9)

Safety Data

• Hazardous Substances Data: 1027400-20-9(Hazardous Substances Data)

Upstream product

• 177976-49-7 3-phenylbenzylamine 

Relevant articles and documents

Indole derivatives as inhibitors or factor Xa

The present invention relates to the inhibition of blood clotting proteins, and more particularly, to indole derivatives of formula (I), in which R1a, R1b, R1cR1d, R2, R3, R4and A are defined as indicated in the claims. The compounds of formula (I) are inhibitors of the blood clotting enzyme factor Xa. The invention also relates to processes for the preparation of the compounds of formula (I), to methods of inhibiting factor Xa activity and of inhibiting blood clotting, to use of the compounds of formula (I) in the treatment and prophylaxis of diseases which can be cured or prevented by the inhibition of factor Xa activity such as thromboembolic diseases, and to the use of the compounds of formula (I) in the preparation of medicaments to be applied in such diseases. The invention further relates to compositions containing a compound of formula (I) in admixture or otherwise in association with an inert carrier, in particular pharmaceutical compositions containing a compound of formula (I) together with pharmaceutically acceptable carrier substances and/or auxiliary substances.