1027408-37-2Relevant articles and documents
Identification of a gene cluster that directs putrebactin biosynthesis in Shewanella species: PubC catalyzes cyclodimerization of N-Hydroxy-N- succinylputrescine
Kadi, Nadia,Arbache, Simon,Song, Lijiang,Oves-Costales, Daniel,Challis, Gregory L.
, p. 10458 - 10459 (2008)
Putrebactin is a dihydroxamate iron chelator produced by the metabolically versatile marine bacterium Shewanella putrefaciens. It is a macrocyclic dimer of N-hydroxy-N-succinyl-putrescine (HSP) and is structurally related to desferrioxamine E, which is a
The preparation of a fully differentiated "multiwarhead" siderophore precursor
Murray, Aaron P.,Miller, Marvin J.
, p. 191 - 194 (2007/10/03)
A protected, fully differentiated siderophore analogue has been prepared so that "Trojan Horse"-like siderophore drug conjugates with different drugs can be synthesized. The key steps in the synthesis include controlled preparation of an unsymmetrical urea and its conversion to a fully differentiated isocyanurate by reaction with chloro(carbonyl) isocyanate.