1027481-27-1

Upstream product

• 1404374-75-9 t-butyl 1-(4-amino-2-fluorophenyl)cyclopropane-1-carboxylate 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 543683-25-6 5(R)-3-[4-[(1-t-butoxycarbonyl)cyclopropan-1-yl]-3-fluorophenyl]-5-hydroxymethyloxazolidin-2-one 

Relevant academic research and scientific papers

CYCLOPROPYL CONTAINING OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF

This invention relates to new oxazolidinones having a cyclopropyl moiety, which are effective against aerobic and anerobic pathogens such as multi-resistant staphylococci, streptococci and enterococci, Bacteroides spp., Clostridia spp. species, as well as acid-fast organisms such as Mycobacterium tuberculosis and other mycobacterial species. The compounds are represented by structural formula I: 1its enantiomer, diastereomer, or pharmaceutically acceptable salt or ester thereof.