1027482-54-7Relevant academic research and scientific papers
A new chiral route to 5- and 6-substituted hydropyran-2-ones utilizing enantiopure 4-cumyloxy-2-cyclopenten-1-one
Sato, Masayuki,Nakashima, Hiromi,Hanada, Keisuke,Hayashi, Masato,Honzumi, Masatoshi,Taniguchi, Takahiko,Ogasawara, Kunio
, p. 2833 - 2837 (2001)
Starting from enantiopure 4-cumyloxy-2-cyclopenten-1-one, a route to 5- and 6-substituted hyropyran-2-ones has been developed. The method has achieved the synthesis of 4,5-cis- and 4,5-trans-5-ethyl-4-hydroxytetrahydropyran-2-ones assigned to marine natural products simplactones. A and B to disprove the former and revise the latter of the proposed structures.
