1027488-86-3Relevant academic research and scientific papers
Potent, highly selective, and non-thiol inhibitors of protein geranylgeranyltransferase-I
Vasudevan, Anil,Qian, Yimin,Vogt, Andreas,Blaskovich, Michelle A.,Ohkanda, Junko,Sebti, Said M.,Hamilton, Andrew D.
, p. 1333 - 1340 (2007/10/03)
The design, synthesis, and biological evaluation of a family of peptidomimetic inhibitors of protein geranylgeranyltransferase-I (PGGTase-I) are reported. The inhibitors are based on the C-terminal CAAL sequence of many geranylgeranylated proteins. Using
