1027498-81-2

Basic information

• Product Name: 4-chloro-3-cyclopentyl-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester
• Synonyms: 4-chloro-3-cyclopentyl-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester
• CAS NO: 1027498-81-2
• Molecular Weight: 307.78
• Mol File: 1027498-81-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-chloro-3-cyclopentyl-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-3-cyclopentyl-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester(1027498-81-2)
• EPA Substance Registry System: 4-chloro-3-cyclopentyl-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester(1027498-81-2)

Safety Data

• Hazardous Substances Data: 1027498-81-2(Hazardous Substances Data)

Upstream product

• 95882-33-0 3-cyclopentyl-3-oxopropanenitrile 

Relevant articles and documents

Discovery of new orally active phosphodiesterase (PDE4) inhibitors

A series of 4-anilinopyrazolopyridine derivatives were synthesized and biologically evaluated as inhibitors of phosphodiesterase (PDE4). Chemical modification of 3, a structurally new chemical lead that was found in our in-house library, was focused on 1- and 3-substituents. Full details of the discovery of a new orally active chemical lead 5 are presented. Structure-activity relationship data, pharmacological evaluation, and the subtype selectivity study are also presented.