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10275-21-5

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10275-21-5 Usage

Description

N,N-Dimethylphenethylamine (hydrochloride) (Item No. 29754) is an analytical reference standard categorized as a phenethylamine. This product is intended for research and forensic applications.

Uses

N,N-Dimethylbenzeneethanamine is used in the synthesis of squalene synthase inhibitors.

Check Digit Verification of cas no

The CAS Registry Mumber 10275-21-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,2,7 and 5 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 10275-21:
(7*1)+(6*0)+(5*2)+(4*7)+(3*5)+(2*2)+(1*1)=65
65 % 10 = 5
So 10275-21-5 is a valid CAS Registry Number.

10275-21-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name N,N-dimethyl-2-phenylethanamine,hydrochloride

1.2 Other means of identification

Product number -
Other names dimethyl-phenethyl-amine,hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:10275-21-5 SDS

10275-21-5Synthetic route

methanol
67-56-1

methanol

3-phenylpropanoyl azide
83421-80-1

3-phenylpropanoyl azide

N,N-Dimethyl-β-phenethylamine Hydrochloride
10275-21-5

N,N-Dimethyl-β-phenethylamine Hydrochloride

Conditions
ConditionsYield
Stage #1: methanol; 3-phenylpropanoyl azide at 100℃; for 20h; Inert atmosphere;
Stage #2: With C54H43ClN3P2Ru(1+)*F6P(1-); potassium carbonate at 140℃; Inert atmosphere;
57%

10275-21-5Downstream Products

10275-21-5Relevant articles and documents

Synthesis of: N -methylated amines from acyl azides using methanol

Chakrabarti, Kaushik,Dutta, Kuheli,Kundu, Sabuj

, p. 5891 - 5896 (2020/08/21)

The transformation of acyl azide derivatives into N-methylamines was developed using methanol as the C1 source via the one-pot Curtius rearrangement and borrowing hydrogen methodology. Following this protocol, various functionalised N-methylated amines were synthesized using the (NNN)Ru(ii) complex from carboxylic acids via an acyl azide intermediate. Several kinetic studies and DFT calculations were carried out to support the mechanism and also to determine the role of the Ru(ii) complex and base in this transformation.

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