10275-21-5 Usage
Description
N,N-Dimethylphenethylamine (hydrochloride) (Item No. 29754) is an analytical reference standard categorized as a phenethylamine. This product is intended for research and forensic applications.
Uses
N,N-Dimethylbenzeneethanamine is used in the synthesis of squalene synthase inhibitors.
Check Digit Verification of cas no
The CAS Registry Mumber 10275-21-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,2,7 and 5 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 10275-21:
(7*1)+(6*0)+(5*2)+(4*7)+(3*5)+(2*2)+(1*1)=65
65 % 10 = 5
So 10275-21-5 is a valid CAS Registry Number.
10275-21-5Relevant articles and documents
Synthesis of: N -methylated amines from acyl azides using methanol
Chakrabarti, Kaushik,Dutta, Kuheli,Kundu, Sabuj
, p. 5891 - 5896 (2020/08/21)
The transformation of acyl azide derivatives into N-methylamines was developed using methanol as the C1 source via the one-pot Curtius rearrangement and borrowing hydrogen methodology. Following this protocol, various functionalised N-methylated amines were synthesized using the (NNN)Ru(ii) complex from carboxylic acids via an acyl azide intermediate. Several kinetic studies and DFT calculations were carried out to support the mechanism and also to determine the role of the Ru(ii) complex and base in this transformation.