1027522-72-0

Basic information

• Product Name: Propane-2-sulfonic acid [2-amino-5-(4-methoxy-benzoyl)-phenyl]-amide
• Synonyms: Propane-2-sulfonic acid [2-amino-5-(4-methoxy-benzoyl)-phenyl]-amide
• CAS NO: 1027522-72-0
• Molecular Weight: 348.423
• Mol File: 1027522-72-0.mol

Chemical Properties

• CAS DataBase Reference: Propane-2-sulfonic acid [2-amino-5-(4-methoxy-benzoyl)-phenyl]-amide(CAS DataBase Reference)
• NIST Chemistry Reference: Propane-2-sulfonic acid [2-amino-5-(4-methoxy-benzoyl)-phenyl]-amide(1027522-72-0)
• EPA Substance Registry System: Propane-2-sulfonic acid [2-amino-5-(4-methoxy-benzoyl)-phenyl]-amide(1027522-72-0)

Safety Data

• Hazardous Substances Data: 1027522-72-0(Hazardous Substances Data)

Upstream product

• 24376-18-9 3,4-dinitrobenzoyl chloride 
• 528-45-0 3,4-dinitrobenzoic acid 

Downstream Products

• 1026649-63-7 [2-Amino-3-(propane-2-sulfonyl)-3H-benzoimidazol-5-yl]-(4-methoxy-phenyl)-methanone 

Relevant articles and documents

Synthesis, antiviral activity, and biological properties of vinylacetylene analogs of enviroxime

A series of vinylacetylene analogs of Enviroxime (1) was synthesized. The new compounds are potent inhibitors of poliovirus in tissue culture. Cross-sensitivity with Enviroxime-derived mutants shows that the new compounds have the same mechanism of action as Enviroxime, which involves the viral 3A protein. In studies with Rhesus monkeys, the p-fluoro derivative 12 was found to be unique in providing oral bioavailability. Metabolism studies using hepatic microsomes suggest that this procedure would be a useful in vitro method for selecting the appropriate animal model for testing oral absorption. Compound 12 was found to be efficacious by oral administration in treating a Coxsackie A21 infection in CD-1 mice.