1027558-83-3

Upstream product

• 170207-97-3 (E)-(2S,3S)-2-[(1R,3aR,4S,7aR)-4-(tert-Butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-6-methoxymethoxy-6-methyl-hept-4-en-3-ol 
• 169951-01-3 Phosphoric acid (E)-(S)-1-{(S)-1-[(1R,3aR,4S,7aR)-4-(tert-butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-ethyl}-4-methoxymethoxy-4-methyl-pent-2-enyl ester diethyl ester 
• 194158-78-6 (1R,3aR,4S,7aR)-1-((E)-(1R,4S)-4-Isopropyl-5-methoxymethoxy-1,5-dimethyl-hex-2-enyl)-7a-methyl-octahydro-inden-4-ol 
• 104651-47-0 (S)-2-[(1R,3aR,4S,7aR)-octahydro-4-[(1,1-dimethylethyl)dimethylsilyloxy]-7a-methyl-1H-inden-1-yl]propanal 
• 194158-90-2 (1R,3aS,7aR)-4-[2-[(3S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohex-(Z)-ylidene]-eth-(E)-ylidene]-1-((E)-(1R,4S)-4-isopropyl-5-methoxymethoxy-1,5-dimethyl-hex-2-enyl)-7a-methyl-octahydro-indene 
• 169951-12-6 tert-Butyl-[(1R,3aR,4S,7aR)-1-((E)-(1R,4S)-4-isopropyl-5-methoxymethoxy-1,5-dimethyl-hex-2-enyl)-7a-methyl-octahydro-inden-4-yloxy]-dimethyl-silane 
• 194158-86-6 (1R,3aR,7aR)-1-((E)-(1R,4S)-4-Isopropyl-5-methoxymethoxy-1,5-dimethyl-hex-2-enyl)-7a-methyl-octahydro-inden-4-one 

Relevant academic research and scientific papers

A Short, Efficient Copper-Mediated Synthesis of 1α,25-Dihydroxyvitamin D2 (1α,25-Dihydroxyergocalciferol) and C-24 Analogs

Two synthetic routes to the nonnatural hormone 1α,25-dihydroxyergocalciferol [2b, 1α,25-(OH)2D2] and analogs modified at C-24 have been developed both starting from aldehyde 7b. Key steps in route A (eight steps, ≈38% overall yield f