102759-40-0Relevant academic research and scientific papers
Catalytic Enantioselective Synthesis of N-C Axially Chiral Sulfonamides through Chiral Palladium-Catalyzed N-Allylation
Kikuchi, Yuki,Nakamura, Chisato,Matsuoka, Mizuki,Asami, Rina,Kitagawa, Osamu
, p. 8112 - 8120 (2019/06/17)
In the presence of (S,S)-Trost ligand and (allyl-Pd-Cl)2 catalyst, the reaction of allyl acetate with the anionic species prepared from various N-(2-tert-butylphenyl)sulfonamides and NaH proceeded in an enantioselective manner (up to 95% ee) to give optically active N-allylated sulfonamide derivatives possessing an N-C axially chiral structure in high yields.
